Journal
DEVELOPMENT
Volume 138, Issue 22, Pages 4819-4830Publisher
COMPANY BIOLOGISTS LTD
DOI: 10.1242/dev.066720
Keywords
Cephalochordates; Vertebrate evolution; Branchiostoma; Amphioxus; Lancelet
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Funding
- Agence Nationale de la Recherche [ANR-2010-BLAN-1716 01, ANR-2010-BLAN-1234 02]
- Association of European Marine Biological Laboratories (ASSEMBLE)
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The phylogenetic position of amphioxus, together with its relatively simple and evolutionarily conserved morphology and genome structure, has led to its use as a model for studies of vertebrate evolution. In particular, the recent development of technical approaches, as well as access to the complete amphioxus genome sequence, has provided the community with tools with which to study the invertebrate-chordate to vertebrate transition. Here, we present this animal model, discussing its life cycle, the model species studied and the experimental techniques that it is amenable to. We also summarize the major findings made using amphioxus that have informed us about the evolution of vertebrate traits.
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