Journal
DEVELOPMENT
Volume 135, Issue 14, Pages 2343-2346Publisher
COMPANY OF BIOLOGISTS LTD
DOI: 10.1242/dev.021279
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Funding
- Medical Research Council [G0500950, G0700711B] Funding Source: researchfish
- MRC [G0500950] Funding Source: UKRI
- Medical Research Council [G0500950] Funding Source: Medline
- NIDDK NIH HHS [R01 DK054077-08, R01 DK054077] Funding Source: Medline
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This essay is about the 1975 JEEM paper by Francoise Dieterlen-Lievre (Dieterlen-Lievre, 1975) and the studies that followed it, which indicated that the adult hematopoietic system in the avian embryo originates, not from the blood islands of the extraembryonic yolk sac as was then believed, but from the body of the embryo itself. Dieterlen-Lievre's 1975 paper created a paradigm shift in hematopoietic research, and provided a new and lasting focus on hematopoietic activity within the embryo body.
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