Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 80, Issue 15, Pages 7779-7784Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b01100
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Funding
- National Basic Research Program of China (973 Program) [2012CB821600]
- Natural Science Foundation of China [21472004, 21332002]
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An efficient and mild synthesis of 9H-fluorene derivatives through a Pd(0)-catalyzed cross-coupling reaction of 1,1-diboronates with 2,2'-dibromobiphenyls has been developed. This reaction features high yields, operational simplicity, and mild reaction conditions, thus providing an excellent alternative to published methods for 9H-fluorene synthesis.
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