Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 80, Issue 14, Pages 7008-7018Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b00719
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- CSIR, New Delhi, India
- IISER Bhopal
- UGC, New Delhi, India
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The enantioselective oxa-Michael reaction of alkoxyboronate strategy was demonstrated to provide a new and practical route to enantioriched 1- and 3-substituted isochromans using a chiral bifunctional organocatalyst. Furthermore, this methodology was extended to the enantioselective synthesis of (+)-sonepiprazole, a dopamine receptor antagonist.
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