Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 80, Issue 21, Pages 11108-11114Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b01745
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Funding
- National Natural Science Foundation of China (NSFC) [21202152]
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A novel and efficient synthesis of pyrrolo[3,2,1-kl]phenothiazines has been developed through a Cu(I)-catalyzed tandem C-S coupling/double cyclization process. Using 2-alkynyl-6-iodoanilines and o-bromobenzenethiols as the starting materials, a wide range of pyrrolo[3,2,1-kl]phenothiazine derivatives were facilely and efficiently generated in one pot under Cu(I) catalysis.
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