Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 80, Issue 15, Pages 7547-7554Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b01126
Keywords
-
Categories
Funding
- 973 project from the MOST of China [2015CB856600]
- NSFC [21272221, 21472179]
- Recruitment Program of Global Experts
- Fundamental Research Funds for the Central Universities [WK 2060190028, 2060190026, 3430000001]
- Fundamental Research Funds for Central Universities
- Cross-disciplinary Collaborative Teams Program for Science, Technology and Innovation from Chinese Academy of Sciences
Ask authors/readers for more resources
A palladium-catalyzed domino cyclization and carboxylation reaction for synthesis of a variety of carboxylic acids was developed, where chloroform was used as carbon monoxide source. The in situ generated neopentylpalladium species by Heck cyclization was efficiently trapped by dichlorocarbene to form a series of carboxylic acids. It was found that in this type of domino reaction CHCl3 is a convenient and safe alternation for CO gas.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available