Journal
DERMATOLOGY
Volume 229, Issue 3, Pages 248-255Publisher
KARGER
DOI: 10.1159/000365075
Keywords
Atopic dermatitis; Eczema score, patient-oriented; Scoring of Atopic Dermatitis index; Self-assessment score; Quality of life; Patient-Oriented Eczema Measure; Self-Administered Eczema Area and Severity Index
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Funding
- A-Derma Laboratories (Pierre Fabre Group, France)
- A-Derma Laboratories
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Objective: Self-assessment scores such as the Patient-Oriented Scoring of Atopic Dermatitis (PO-SCORAD) index being recommended by public health authorities for chronic disease management, we aimed at analysing correlations between PO-SCORAD and physician and patient assessment scores of atopic dermatitis (AD) severity and quality of life. Methods: We perfomed an observational study conducted in 12 European countries in 4,222 atopic patients aged 1 month and prescribed Exomega (R) emollient cream. AD severity was measured by the SCORAD index, PO-SCORAD, Patient-Oriented Eczema Measure (POEM) and Self-Administered Eczema Area and Severity Index (SA-EASI) scales, and patient and family quality of life by the Dermatology Life Quality Index (DLQI) and Dermatitis Family Questionnaire Impact (DFQI) scales, respectively. Their correlations were analysed. Results: PO-SCORAD was the only self-assessment score to be highly correlated with the SCORAD index and POEM (r >= 0.70). It was also the best correlated with the DLQI (r = 0.67) and DFQI (r = 0.56). After a 5-week treatment, SCORAD index and PO-SCORAD severity scores had decreased significantly by 60 and 56% (p < 0.0001), and quality of life had improved. Conclusion: PO-SCORAD is better correlated with quality of life scales than other self-assessment scores. (C) 2014 S. Karger AG, Basel
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