Journal
DERMATOLOGIC CLINICS
Volume 29, Issue 3, Pages 511-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.det.2011.03.006
Keywords
Pemphigus vulgaris; Paronychia; Onychomadesis; Onycholysis; Bullous pemphigoid; Pterygium
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Autoimmune bullous disorders frequently cause nail abnormalities, particularly paronychia and onychomadesis. In pemphigus vulgaris (PV) nail abnormalities can even precede skin findings. Nail lesions often relapse just before generalized disease exacerbation or recurrence. Severe nail changes are often associated with extensive and severe disease. Fingernails are more commonly affected. A report in the literature associates hemorrhagic nail abnormalities with poor prognosis in patients with PV. Nail scarring and pterygium are a rare complication of bullous pemphigoid. Nail loss has been occasionally reported in epidermolysis bullosa acquisita.
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