Journal
DERMATITIS
Volume 23, Issue 5, Pages 203-209Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/DER.0b013e31826e4591
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Funding
- Leo Pharma Research Foundation
- Else and Mogens Wedell-Wedellsborgs Foundation
- Jacob Madsen and wife Olga Madsens Foundation
- Gerhard Brondsteds travel grant
- Danish physician's insurance under Codan/SEB Pension
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This clinical review article presents clinical and scientific data on cobalt sensitization and dermatitis. It is concluded that cobalt despite being a strong sensitizer and a prevalent contact allergen to come up on patch testing should be regarded as a very complex metal to test with. Exposure data together with clinical data from metal workers heavily exposed to cobalt suggest that patch-test reactions are sometimes false positive and that patch testers should carefully evaluate their clinical relevance.
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