4.7 Article

Anti-Markovnikov oxidation and hydration of terminal olefins

Journal

DALTON TRANSACTIONS
Volume 43, Issue 19, Pages 6952-6964

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3dt53600a

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Funding

  1. National University of Singapore
  2. ASTAR [R143-000-523-133, R143-000-535-305]
  3. ASTAR SERC for a postdoctoral grant [PSF R143-000-535-305]

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Efficient syntheses of aldehydes and primary alcohols from terminal olefins are critical to the chemical laboratory and industry. Heavy emphasis has been placed on regioselective olefin functionalization in recent decades. This perspective mainly focuses on advances in the Wacker-type oxidation and tandem hydration of terminal olefins with anti-Markovnikov selectivity.

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