Journal
DALTON TRANSACTIONS
Volume 42, Issue 18, Pages 6252-6276Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3dt50268f
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- Greek national funds (National Strategic Reference Framework (NSRF))
- European Social Fund (ESF)
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The structural features of copper(II), nickel(II), cobalt(II) and zinc(II) complexes with the antimicrobial drugs quinolones and non-steroidal anti-inflammatory drugs (NSAIDs) as ligands are discussed. The binding properties of these complexes to biomolecules (calf-thymus DNA, bovine or human serum albumin) are presented and evaluated. The biological activity (antimicrobial, antioxidant and antiproliferative) of selected complexes is investigated. Further perspectives concerning the synthesis and the biological activity of novel complexes with quinolones or NSAIDs attractive to synthetic chemists, biochemists and/or biologists are presented.
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