4.7 Article

BODIPY-phosphane as a versatile tool for easy access to new metal-based theranostics

Journal

DALTON TRANSACTIONS
Volume 42, Issue 17, Pages 6102-6109

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2dt32055j

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Funding

  1. Conseil Regional de Bourgogne
  2. Ministere de l'Enseignement Superieur et de la Recherche
  3. Centre National de la Recherche Scientifique (CNRS)
  4. University of Groningen

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A new BODIPY-phosphane was synthesized and proved to be a versatile tool for imaging organometallic complexes. It also led to easy access to a new family of theranostics, featuring gold, ruthenium and osmium complexes. The compounds' cytotoxicity was tested on cancer cells, and their cell uptake was followed by fluorescence microscopy in vitro.

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