Journal
DALTON TRANSACTIONS
Volume 41, Issue 23, Pages 6906-6909Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2dt30357d
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Funding
- NNSF of China [21001022]
- National Grand Fundamental Research 973 Program of China [2010CB635114]
- Program for New Century Excellent Talents in Chinese University [NCET-10-0282]
- PhD Station Foundation of Ministry of Education [20100043110003]
- Foundation for Author of National Excellent Doctoral Dissertation of P.R. China (FANEDD) [201022]
- Science and Technology Development Planning of Jilin Province [201001169, 20100182]
- Fundamental Research Funds for the Central Universities [09QNJJ018, 09ZDQD003, 10CXTD001]
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Zeolitic Imidazolate Framework-8 (ZIF-8), for the first time for ZIFs, exhibits a remarkable capacity for the anticancer drug 5-fluorouracil (5-FU), around 660 mg of 5-FU/g of ZIF-8, and presents a pH-triggered controlled drug release property. These prove ZIF-8 to be a valuable candidate for delivery of anticancer agents and reveal its potential applications in the treatment of cancer.
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