Journal
DALTON TRANSACTIONS
Volume 40, Issue 5, Pages 1024-1027Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0dt01607a
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Funding
- Irish Technological Sector Research Strand III programme [CRS02-TA01]
- Dublin Institute of Technology
- Higher Education Authority of Ireland
- Irish National Development Plan
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Three, structurally characterised, bis-phen Cu(II) complexes of the phthalate isomers display rapid, low micromolar in vitro cytotoxicity against a range of epithelial tumour cells. The complexes induce relaxation of supercoiled plasmid DNA in the absence of external reducing agents and display efficient CT-DNA, Poly[d(A-T)](2) and Poly[d(G-C)](2) binding.
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