4.7 Article

A ratiometric fluorescent probe for oxalate based on alkyne-conjugated carboxamidoquinolines in aqueous solution and imaging in living cells

Journal

DALTON TRANSACTIONS
Volume 40, Issue 5, Pages 1034-1037

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0dt01364a

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Funding

  1. National Natural Science Foundation of China [90713026, 21076077]
  2. Key New Drug Creation and Manufacturing Program [2009ZX09103-102]
  3. Shanghai Leading Academic Discipline Project [B507]

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A novel ratiometric fluorescent probe for oxalic acid was designed and synthesized, based on the zinc-containing [DAQZ@2Zn(2+)] complex. It shows highly selective on-off fluorescence changes with a more than 20 nm blue shift in wavelength for oxalic acids in aqueous solution. Moreover, it can fluorescently respond to oxalic acid in living cells.

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