4.7 Article

A new rhodamine-based chemosensor for Cu2+ and the study of its behaviour in living cells

Journal

DALTON TRANSACTIONS
Volume 39, Issue 34, Pages 7894-7896

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0dt00606h

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Funding

  1. Foundation of State Key Laboratory of Applied Organic Chemistry
  2. NSFC [20171019]

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A new rhodamine-based chemosensor (L1) was synthesized, and it exhibits high sensitivity and selectivity for the copper cation over other commonly coexistent metal ions in aqueous solution. Upon the addition of Cu2+, the spirolactam ring of L1 was opened and a 1 : 1 metal-ligand complex was formed. Fluorescent imaging of Cu2+ in living cells is also successfully demonstrated.

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