4.7 Article

1,10-Phenanthroline platinum(II) complex: a simple molecule for efficient G-quadruplex stabilization

Journal

DALTON TRANSACTIONS
Volume 39, Issue 31, Pages 7214-7216

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0dt00211a

Keywords

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Funding

  1. Fundamental Research Funds for the Central Universities
  2. National Natural Science Foundation of China [20821001, 20831006, 20725103, 30770494]
  3. Guangdong Provincial Natural Science Foundation [9351027501000003]
  4. 973 Program [2007CB815306]

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Two simple complexes [Pt(phen)(2)](PF6)(2) and [Pt(bpy)(2)](PF6)(2) exhibit high stabilization potential for G-quadruplex DNA with [Pt(phen)(2)](PF6)(2) possessing higher capability due to its greater planarity.

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