A new chiral di-N-heterocyclic carbene (NHC) cyclophane ligand and its application in palladium enantioselective catalysis

This report details the synthesis and characterization of the first chiral diNHC cyclophane ligand and its palladium allyl complex. The complex was tested for 1,4-conjugate addition of phenylboronic acid to 2-cyclohexen-1-one and provides R-3-phenylcyclohexanone in 50% enantiomeric excess.