Journal
CYTOTHERAPY
Volume 12, Issue 6, Pages 721-734Publisher
ELSEVIER SCI LTD
DOI: 10.3109/14653241003774045
Keywords
dendritic cells; cancer vaccination; malignant melanoma; regulatory T cells
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Background and Aim: Dendritic cells are regarded as the most effective antigen presenting cells and coordinators of the immune response and therefore suitable as vaccine basis. Here we present results from a clinical study in which patients with malignant melanoma (MM) with verified progressive disease received vaccination with autologous monocyte-derived mature dendritic cells (DC) pulsed with p53, survivin and telomerase-derived peptides (HLA-A2
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