Journal
CURRENT TOPICS IN MEDICINAL CHEMISTRY
Volume 8, Issue 2, Pages 101-113Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/156802608783378837
Keywords
N-glycosyl amine; N-glycosyl amide; N-glycosylated heterocycles
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Interest in the chemistry and biological properties of non-nucleoside N-glycosidic compounds has gathered pace over the past several years; the occurrence of the N-glycoside moiety in glycoproteins and a range of active natural products has prompted the synthesis of a diverse spectrum of related materials with promising potential in medicinal chemistry. Particularly prominent has been the synthesis of novel N-glycosyl amides, 1,2,3-triazoles, and progress in the construction and diversification of natural products such as the mannopeptimycins and indolocarbazoles, each of which are discussed in this article.
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