Journal
CURRENT PHARMACEUTICAL BIOTECHNOLOGY
Volume 12, Issue 4, Pages 459-468Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138920111795163904
Keywords
Drug discovery and development process; molecular imaging; drug screening; pharmacokinetic study; preclinical and clinical study; personalized medicine; lesionalized medicine
Funding
- Biomedical Research Institute, Kyungpook National University Hospital
- National Research Foundation of Korea [2009-50379] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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The process of drug discovery and development requires enormous resources and time, with increasing cost for new drug development. Molecular imaging techniques have tremendous potential for improving the efficiency of drug screening, assessing the pharmacokinetics of new drugs, and evaluating drug effects. Appropriate application of molecular imaging to drug discovery and development can markedly reduce costs and the time required for new drug development. This review focuses on the contributions of molecular imaging for drug discovery and development, particularly drug screening, pharmacokinetic, preclinical and clinical drug evaluation, and for personalized and lesionalized medicine.
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