4.3 Article

Stereoselective Synthesis of α-Aminophosphonic Acids Analogs of the 20 Proteinogenic α-Amino Acids

Journal

CURRENT ORGANIC SYNTHESIS
Volume 9, Issue 3, Pages 310-341

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157017912801270595

Keywords

alpha-Aminophosphonic acids; alpha-aminophosphonates; alpha-amino acids; stereoselective synthesis; biological activity; resolution

Funding

  1. CONACYT-MEXICO [62271]
  2. Ministerio de Educacion y Ciencia-FEDER [CTQ2007-62245]
  3. Gobierno de Aragon [E40]
  4. CONACYT-CSIC [J000.400/2009, 2008MX0044]

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This review describes the synthesis, biological interest and importance of the alpha-aminophosphonic acids analogs of the 20 proteinogenic alpha-amino acids. Special attention is devoted to those stereoselective procedures that allow the synthesis of the required compounds in enantiomerically pure form.

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