Journal
CURRENT ORGANIC SYNTHESIS
Volume 8, Issue 4, Pages 488-497Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157017911796117188
Keywords
Bioluminescence imaging; Molecular Imaging; Probe; Luciferase
Categories
Funding
- NIH/NCI [R01 CA119053, R01CA128908, R21CA121842]
Ask authors/readers for more resources
Bioluminescence refers to the emission of light from a living system in which photoproteins such as luciferase enzymes oxidize their substrates to produce light. Because of its high-sensitivity and low-toxicity, bioluminescence imaging (BLI) is particularly useful for in vitro assays and in vivo small animal imaging. It provides a powerful tool to study various important biological questions and processes including gene and protein expression, protein-protein interactions, protein-nucleic acid interactions, and cell signaling pathway functions. This review highlights some of the latest developments in the design and applications of molecular probes for BLI.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available