4.3 Review

Bifunctional Chiral Organocatalysts in Organic Transformations

Journal

CURRENT ORGANIC SYNTHESIS
Volume 6, Issue 4, Pages 380-399

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157017909789108710

Keywords

Asymmetric organocatalysis; axially chiral binaphthyl; Bronsted acid catalyst; chiral thiourea; absolute configuration; synthesis

Funding

  1. National Key Program for Basic Research [2003CB114404]
  2. National Natural Science Foundation of China [20872021]

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In continuation to our earlier review, we report herein further development on the organocatalytic approach for the synthesis of enantioenriched organic compounds. Application of synthetic bifunctional chiral organocatalysts with emphasis on Bronsted acid catalyst derived from chiral phosphoric acid derivative, and mechanism of asymmetric catalysis are discussed.

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