4.5 Article

Environment-friendly Synthesis of Bioactive Pyrazoles

Journal

CURRENT ORGANIC CHEMISTRY
Volume 18, Issue 1, Pages 115-126

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/13852728113179990029

Keywords

Pyrazoles; green synthesis; bioactivity

Funding

  1. CNPq
  2. FAPERGS
  3. CAPES
  4. Secretaria da Ciencia e Tecnologia do Estado do Rio Grande do Sul

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Pyrazoles are compounds of synthetic origin, and constitute a group of nitrogen heterocyclic compounds that have shown several biological activities. Their transformations into other biologically active molecules have been exploited since the early 1960s. This review describes the work on the environment-friendly synthesis of bioactive pyrazoles. The review covers mainly the data published over the last five years (2007-2012).

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