Journal
CURRENT ORGANIC CHEMISTRY
Volume 16, Issue 12, Pages 1512-1539Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138527212800672583
Keywords
Diterpenoid; Cembrane; Natural product; Biological activity
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Funding
- National Basic Research Program of China (973 Program) [2010CB833800, 2011CB915503]
- Chinese Academy of Science [KSCX2-YW-G-073, KSCX2-EW-G-12B]
- National Natural Science Foundation of China [30973679, 21172230, 21002110]
- Guangdong Province-CAS [2011B090300023]
- National High Technology Research and Development Program of China (863 Program) [2012AA092104]
- Guangdong Province Marine and Fishery Special Project for Science and Technology Popularization [A201101F03]
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Cembrane-type diterpenoids are a large and structurally varied group of natural products isolated from both terrestrial and marine organisms. The present paper reviews all the metabolites of cembrane diterpenes, reported up to 2010. The natural products discussed in this review can be divided into several different structural families featuring a variety of ring sizes and oxidation patterns. The currently known biological activities will be presented as well.
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