4.5 Article

Recent Advances in the Chemistry of Pyrazoles. Properties, Biological Activities, and Syntheses

Journal

CURRENT ORGANIC CHEMISTRY
Volume 15, Issue 9, Pages 1423-1463

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138527211795378263

Keywords

Condensation; Diazo Compounds; 1,3-Dipolar Cycloaddition; Hydrazines; N-Heterocyclic Carbene; Natural Products; Rearrangement; Regiochemistry

Funding

  1. Deutsche Forschungsgemeinschaft

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Pyrazoles are of considerable interest due to the broad variety of their biological activities. This overview summarizes structures of pharmacologically interesting pyrazoles, natural products, technically applied pyrazoles as well as pyrazole syntheses published during the last decade. In addition, new insights into the properties such as tautomerisms, conformations, pyrolyses and decomposition reactions of pyrazoles are reviewed.

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