Journal
CURRENT ORGANIC CHEMISTRY
Volume 15, Issue 5, Pages 657-674Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138527211794519005
Keywords
Pyrazole; regioselective dipolar cycloaddition; regioselective condensation; regioselective cross-coupling
Categories
Funding
- National Research Foundation of Korea
Ask authors/readers for more resources
Pyrazole is the ubiquitous sub-structure of many natural products and biologically active compounds. In this respect, its regioselective synthesis drew a lot of attention from synthetic organic chemists, leading to the development of various regioselective modifications of the classical Knorr cyclocondensation reaction and alternative methods. This review covers the period of 2003 to the middle of 2009 on the regioselective synthesis of pyrazoles, which are categorized into four reaction types: (i) modified Knorr condensation reaction using 1,3-dicarbonyl surrogates; (ii) 1,3-dipolar cycloadditions approach; (iii) regioselective direct substitution reaction of the pyrazole ring system; and (iv) other methods.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available