4.5 Article

Palladium-Catalyzed Oxidative Heck Reaction

Journal

CURRENT ORGANIC CHEMISTRY
Volume 15, Issue 18, Pages 3362-3388

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138527211797248030

Keywords

Palladium-catalyzed; oxidative Heck reaction; organometallic compounds; olefins; transmetallation; base; ligand; oxidant

Funding

  1. Peking University
  2. National Science Foundation of China [20702002, 0872003]
  3. National Basic Research Program of China (973 Program) [2009CB825300]
  4. Program for NCET
  5. Ph.D. Programs Foundation of Ministry of Education of China [20070001808]

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This review presents the development of Palladium-catalyzed oxidative Heck reactions of organometallic compounds (OMCs) with alkenes. The mechanism is discussed with many experimental studies. OMCs derived from Group III to Group VII are shown to be efficient substrates for the oxidative Heck reaction.

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