Journal
CURRENT OPINION IN STRUCTURAL BIOLOGY
Volume 23, Issue 5, Pages 748-754Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.sbi.2013.06.007
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Funding
- European Community under BioStruct-X [283570]
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The advances made in small and wide angle X-ray scattering over the past decades have had a large impact on structural biology. Many new insights into challenging biological probes including large and transient complexes, flexible macromolecules as well as other exciting objects of various sizes were gained with this low resolution technique. Here, we review the recent developments in the experimental setups and in software for data collection and analysis, specifically for hybrid approaches. These progresses have allowed scientists to address a number of intriguing questions which could not be answered with other structural methods alone.
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