Journal
CURRENT OPINION IN STRUCTURAL BIOLOGY
Volume 19, Issue 3, Pages 335-340Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.sbi.2009.03.007
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Funding
- Complexity Science [GR2006-018]
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Proteins in their evolution appear to follow several discrete stages, which is reflected in their modular organization. The sequences of the protein modules are highly variable while their functions and structures are rather conserved. The relatedness of the variable sequences is well represented by the networks in natural protein sequence space that also suggests evolutionary connections.
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