Journal
CURRENT OPINION IN STRUCTURAL BIOLOGY
Volume 18, Issue 4, Pages 507-515Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.sbi.2008.05.008
Keywords
-
Categories
Funding
- NIGMS NIH HHS [R01 GM080515-01, R01 GM080515] Funding Source: Medline
Ask authors/readers for more resources
Repeat proteins contain tandem arrays of small structural motifs. As a consequence of this architecture, they adopt non-globular, extended structures that present large, highly specific surfaces for ligand binding. Here we discuss recent advances toward understanding the functional role of this unique modular architecture. We showcase specific examples of natural repeat proteins interacting with diverse ligands and also present examples of designed repeat protein-ligand interactions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available