Journal
CURRENT OPINION IN PLANT BIOLOGY
Volume 16, Issue 3, Pages 335-343Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.pbi.2013.01.004
Keywords
-
Categories
Funding
- Max-Planck-Society
- Deutsche Forschungsgemeinschaft [DFG-SFB429]
- National Council for Scientific and Technological Development CNPq-Brazil [478261/2010-1, 472787/2011-0]
Ask authors/readers for more resources
Recent years have seen considerable advances in our understanding of the particular physiological roles of the constituent enzymes of the tricarboxylic acid (TCA) cycle. Despite acquiring a fairly comprehensive overview of the functional importance of these proteins relatively little is known concerning how this important pathway is regulated. In this review we concentrate on the mitochondrial reactions since this organelle is the only one in which a full cycle can, at least theoretically, operate. We summarize what is known about the regulation of the enzymes of the pathway both from historical kinetic studies as well as discussing more recent transcriptional and proteomic studies and our enhanced understanding of subcellular compartmentation within the context of metabolic regulation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available