Journal
CURRENT OPINION IN PLANT BIOLOGY
Volume 16, Issue 3, Pages 350-357Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.pbi.2013.02.009
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Funding
- National Science Foundation [MCB-0843312, MCB-1158500]
- BBSRC (UK)
- Div Of Molecular and Cellular Bioscience
- Direct For Biological Sciences [0843312, 1158500] Funding Source: National Science Foundation
- BBSRC [BBS/E/C/00005207] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BBS/E/C/00005207] Funding Source: researchfish
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Plant sphingolipids are structurally diverse molecules that are important as membrane components and bioactive molecules. An appreciation of the relationship between structural diversity and functional significance of plant sphingolipids is emerging through characterization of Arabidopsis mutants coupled with advanced analytical methods. It is increasingly apparent that modifications such as hydroxylation and desaturation of the sphingolipid nonpolar long-chain bases and fatty acids influence their metabolic routing to particular complex sphingolipid classes and their functions in signaling pathways and other cellular processes, such as membrane protein targeting. Here, we review recent reports investigating some of the more prevalent sphingolipid structural modifications and their functional importance in plants.
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