Journal
CURRENT OPINION IN PLANT BIOLOGY
Volume 16, Issue 1, Pages 62-69Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.pbi.2012.12.002
Keywords
-
Categories
Funding
- EMBO long-term fellowship
- HFSP long-term fellowship
- National Human Genome Research Institute [T32 HG00035]
- National Science Foundation [DGE-0718124, MCB-1242744]
- National Institute of Health [DP2OD008371]
- Direct For Biological Sciences
- Div Of Molecular and Cellular Bioscience [1242744] Funding Source: National Science Foundation
Ask authors/readers for more resources
Robustness, the ability of organisms to buffer phenotypes against perturbations, has drawn renewed interest among developmental biologists and geneticists. A growing body of research supports an important role of robustness in the genotype to phenotype translation, with far-reaching implications for evolutionary processes and disease susceptibility. Similar to animals and fungi, plant robustness is a function of genetic network architecture. Most perturbations are buffered; however, perturbation of network hubs destabilizes many traits. Here, we review recent advances in identifying molecular robustness mechanisms in plants that have been enabled by a combination of classical genetics and population genetics with genome-scale data.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available