4.7 Review

The emergence of whole genome association scans in barley

Journal

CURRENT OPINION IN PLANT BIOLOGY
Volume 12, Issue 2, Pages 218-222

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/j.pbi.2008.12.007

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Funding

  1. Association Genetics of Elite UK Barleys [SA LINK 302/BB/D522003/1]
  2. BBSRC [BB/D522003/1] Funding Source: UKRI
  3. Biotechnology and Biological Sciences Research Council [BB/D522003/1] Funding Source: researchfish

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Barley geneticists are currently using association genetics to identify and fine map traits directly in elite plant breeding material. This has been made possible by the development of a highly parallel SNP assay platform that provides sufficient marker density for genome-wide scans and linkage disequilibrium-led gene identification. By leveraging the combined resources of the barley research and breeding sectors, marker-trait associations are being identified and a renewed interest has emerged in novel strategies for barley improvement. New database and visualization tools have been developed and statistical methods adapted from human genetics to account for complexities in the datasets. Exciting early results suggest that association genetics will assume a central role in establishing genotype-to-phenotype relationships.

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