Journal
CURRENT OPINION IN PLANT BIOLOGY
Volume 11, Issue 5, Pages 486-494Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.pbi.2008.06.003
Keywords
-
Categories
Funding
- Ministerio de Educacion y Ciencia of Spain
- Comunidad de Madrid
- European Commission
- EMBO
- Portuguese FCT
Ask authors/readers for more resources
Jasmonates (JAs) are essential hormones for plant defense and development. In spite of their importance, the molecular details of their signaling pathways remain largely unknown. A new family of regulators of JA signaling named JAZ, jasmonate ZIM-domain proteins, has recently been described. JAZ proteins repress of JA signaling and are targeted by the E3-ubiquitin ligase SCFCOI1 for proteasome degradation in response to JA. Hormone binding depends on a functional COI1 protein suggesting that COI1 is the JA receptor. MYC2, a positive regulator of JA-dependent responses, has been identified as a target of JAZ repressors. Interestingly, MYC2 and JAZ proteins are involved in a negative regulatory feedback loop, suggesting a model to explain how transcriptional reprogramming is turned on and off in response to JA. The discovery of JAZ repressors provides a new framework to understand JA-signaling pathways from hormonal perception to transcriptional activation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available