Journal
CURRENT OPINION IN PHARMACOLOGY
Volume 42, Issue -, Pages 111-121Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.coph.2018.08.007
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Funding
- ISCIII-FEDER [CPII16/00026]
- EU H2020 Programme [681002, 676559]
- IMI2-JU [116030, 777365]
- EU-H2020
- ISCIII
- FEDER
- MINECO [MDM-2014-0370]
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The use and utility of computational models in drug development has significantly grown in the last decades, fostered by the availability of high throughput datasets and new data analysis strategies. These in silico approaches are demonstrating their ability to generate reliable predictions as well as new knowledge on the mode of action of drugs and the mechanisms underlying their side effects, altogether helping to reduce the costs of drug development. The aim of this review is to provide a panorama of developments in the field in the last two years.
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