Journal
CURRENT OPINION IN PHARMACOLOGY
Volume 13, Issue 3, Pages 331-336Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.coph.2013.04.010
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Funding
- Asthma UK [MRC-Asthma UK Centre] Funding Source: researchfish
- Medical Research Council [G1000758B, G1000758] Funding Source: researchfish
- Medical Research Council [G1000758] Funding Source: Medline
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Asthma is the most common chronic respiratory disease and its prevalence is on the increase. Respiratory viral infections in early life have been suggested to increase the risk of development of asthma in later life and virus infection remains the single greatest precipitant of asthma exacerbations. The development of effective anti-viral treatments remains a key target for therapeutic intervention. Here we discuss the role of respiratory viral infection in asthma exacerbation and highlight current and potential anti-viral agents and their mechanisms of action.
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