Journal
CURRENT OPINION IN ORGAN TRANSPLANTATION
Volume 18, Issue 2, Pages 191-196Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MOT.0b013e32835f0771
Keywords
hepatocyte growth factor; kidney; regenerative medicine; stem cells; transplantation
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Funding
- FP7 project RegenerAR
- Ministerio Ciencia e Innovacion-ISCIII [PI061073, PS09/01630]
- European Union grant [SysKid project, Framework Programme 7 (FP7)]
- ISCIII-RETIC [REDinREN/RD06/0016]
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Purpose of review To briefly show which are the mechanisms and cell types involved in kidney regeneration and describe some of the therapies currently under study in regenerative medicine for kidney transplantation. Recent findings The kidney contains cell progenitors that under specific circumstances have the ability to regenerate specific structures. Apart from the knowledge gained in the self-regenerative properties of the kidney, new concepts in regenerative medicine such as organ engineering and the use of mesenchymal stem cell-based therapies are currently the focus of attention in the field. Summary Overall, kidney regeneration is a reality and the knowledge on how to control it will be one of the main scopes in the present and future.
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