Journal
CURRENT OPINION IN OBSTETRICS & GYNECOLOGY
Volume 25, Issue 3, Pages 173-180Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/GCO.0b013e3283609138
Keywords
B-vitamins; docosahexaenoic acid; fertility; folic acid; micronutrients; selenium; vitamin C
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Purpose of review Benefit of micronutrient supplementation on female fertility. Recent findings Reports of randomized trials are rare. Most studies are focused on multivitamin supplementations. For some micronutrients, a positive impact on fertility could be shown. This article reviews the available clinical studies as well as the pathophysiological background of possible effects and summarizes the potential benefits of selected micronutrients on female fertility. Summary Apart from lowering the malformation risk by periconceptional supplementation of folic acid, substitution with different micronutrients, particularly folic acid, vitamin B6, vitamin C, vitamin D, vitamin E, iodine, selenium, iron, and DHA might have a positive impact on infertility treatment. The multivitamin formulation should take the pathophysiology, clinical studies, and upper limits into account.
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