Journal
CURRENT OPINION IN NEUROBIOLOGY
Volume 23, Issue 4, Pages 639-648Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2013.01.002
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Funding
- Intramural NIH HHS [Z99 DA999999] Funding Source: Medline
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Through sequential waves of drug-induced neurochemical stimulation, addiction co-opts the brain's neuronal circuits that mediate reward, motivation to behavioral inflexibility and a severe disruption of self-control and compulsive drug intake. Brain imaging technologies have allowed neuroscientists to map out the neural landscape of addiction in the human brain and to understand how drugs modify it.
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