4.5 Review

Physiological and circuit mechanisms of postural control

Journal

CURRENT OPINION IN NEUROBIOLOGY
Volume 22, Issue 4, Pages 646-652

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2012.03.002

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Funding

  1. Swedish Research Council [11554, 21076]
  2. Christopher and Dana Reeve Foundation
  3. NIH [NS064964]

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The postural system maintains a specific body orientation and equilibrium during standing and during locomotion in the presence of many destabilizing factors (external and internal). Numerous studies in humans have revealed essential features of the functional organization of this system. Recent studies on different animal models have significantly supplemented human studies. They have greatly expanded our knowledge of how the control system operates, how the postural functions are distributed within different parts of CNS, and how these parts interact with each other to produce postural corrections and adjustments. This review outlines recent advances in the studies of postural control in quadrupeds, with special attention given the neuronal postural mechanisms.

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