Journal
CURRENT OPINION IN NEUROBIOLOGY
Volume 21, Issue 3, Pages 402-407Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2011.04.002
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Funding
- Netherlands Organization for Scientific Research [RGP0036/2009-C]
- Netherlands Brain Foundation
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Dopamine has long been implicated in a wide variety of high-level cognitive processes, ranging from working memory to rule learning and attention switching. Notable progress has been made in the past decades, but the mechanisms underlying effects of dopamine on high-level cognition remain unclear. This article reviews evidence for an important role of the striatum and its interaction with the prefrontal cortex and suggests a variety of ways by which changes in dopamine transmission can bias high-level cognition.
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