4.5 Review

Neural and behavioral mechanisms of olfactory perception

Journal

CURRENT OPINION IN NEUROBIOLOGY
Volume 18, Issue 4, Pages 408-412

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2008.08.015

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Funding

  1. NIH [1R01DC008174-01]
  2. Pew Scholar Award
  3. McKnight Scholar Award
  4. Sloan Foundation

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Recent in vivo and in vitro studies have challenged existing models of olfactory processing in the vertebrate olfactory bulb and insect antennal lobe. Whereas lateral connectivity between olfactory glomeruli was previously thought to form a dense, topographically organized inhibitory surround, new evidence suggests that lateral connections may be sparse, nontopographic, and partly excitatory. Other recent studies highlight the role of active sensing (sniffing) in shaping odor-evoked neural activity and perception.

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