Journal
CURRENT OPINION IN MICROBIOLOGY
Volume 18, Issue -, Pages 61-67Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.mib.2014.02.003
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Funding
- Swedish Research Council
- Knut and Alice Wallenberg Foundation (Wallenberg Scholar)
- ERC
- Swedish Cancer Society
- Stiftelsen Olle Engkvist Byggmastare Foundation
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In the process of yeast budding, an aged and deteriorated mother cell gives rise to a youthful and pristine daughter cell. This remarkable event offers a tractable model system for identifying factors affecting life expectancy and it has been established that multiple aging factors operate in parallel. Herein, we will highlight the identity of such aging factors, how they are asymmetrically segregated, and whether the knowledge of their deteriorating effects might be utilized to approach cellular and tissue rejuvenation in metazoans, including humans.
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