Journal
CURRENT OPINION IN MICROBIOLOGY
Volume 15, Issue 6, Pages 653-659Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.mib.2012.10.002
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- Deutsche Forschungsgemeinschaft (DFG) [Tu50-17]
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Reactive oxygen species (ROS) generated by NADPH-dependent oxidases (Nox) have been shown to function as signaling molecules and to be essential for many differentiation processes in mammals and plants. There is growing evidence that ROS are important for many aspects of fungal life including vegetative hyphal growth, differentiation of conidial anastomosis tubes, fruiting body and infection structure formation, and for induction of apoptosis. Recent results from studies in fungal saprophytic and pathogenic model systems have shed new light on the role of Nox in cytoskeleton organization, the structure of Nox complexes and links to components of the apical complex, and the localization of Nox to the endoplasmic reticulum.
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