Journal
CURRENT OPINION IN MICROBIOLOGY
Volume 13, Issue 4, Pages 530-539Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.mib.2010.05.011
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Funding
- Croatian Ministry of Science [0621261-1263, 0621261-1268]
- EU [CAPRI2010]
- NIH [1R01AI083201-01]
- Howard Hughes Medical Institute
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Since their discovery, our understanding of NK cells has evolved from branding them marginal innate immunity cells to key players in anti-viral and anti-tumor immunity. Importance of NK cells in control of various viral infections is perhaps best illustrated by the existence of plethora of viral mechanisms aimed to modulate their function These mechanisms include not only virally encoded immunoevasion proteins but also viral miRNA Moreover, the evidence has been accumulated supporting the role of viral immunoevasion of NK cells in viral pathogenesis in vivo.
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