Journal
CURRENT OPINION IN CRITICAL CARE
Volume 16, Issue 4, Pages 297-308Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MCC.0b013e32833be8b3
Keywords
colloid therapy; crystalloid therapy; fluid therapy; sepsis; septic shock; severe sepsis
Categories
Funding
- NIH
Ask authors/readers for more resources
Purpose of review To examine the role of fluid therapy in the pathogenesis of severe sepsis and septic shock. The type, composition, titration, management strategies and complications of fluid administration will be examined in respect to outcomes. Recent findings Fluids have a critical role in the pathogenesis and treatment of early resuscitation of severe sepsis and septic shock. Summary Although this pathogenesis is evolving, early titrated fluid administration modulates inflammation, improves microvascular perfusion, impacts organ function and outcome. Fluid administration has limited impact on tissue perfusion during the later stages of sepsis and excess fluid is deleterious to outcome. The type of fluid solution does not seem to influence these observations.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available