Journal
CURRENT OPINION IN COLLOID & INTERFACE SCIENCE
Volume 13, Issue 6, Pages 389-394Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.cocis.2007.10.004
Keywords
Virus; Capsid; dsDNA; ssRNA; Modelling; Spool structure; Thermodynamics; Self-assembly
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Theoretical and simulation investigations of viruses attaining icosahedral shape based on molecular models have recently become an exciting and rapidly growing research area. We discuss recent studies addressing the packing of the genome inside the capsid, thermodynamics, and the self-assembly of capsids. Special attention is given to the different packing of double-stranded and single-stranded polynucleotides in the viral capsid and its consequences. (C) 2007 Elsevier Ltd. All rights reserved.
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